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Description

GLP-1 agonists for weight loss: What you need to know | MDedge

272 participants randomized. Baseline Mean body weight : 108.7 kg Mean weight loss at week 26: 8.6% to 12.6% orforglipron dose cohorts 2.0% in the placebo group. Daily oral orforglipron, a nonpeptide

In the ATTAIN-1 phase 3, randomized trial, the use of orforglipron, an oral glucagon-like peptide-1 receptor agonist, led to significant mean body-weight reductions in patients with obesity, as compared with placebo. Full

Late breaking at #ADA2023: In this 36-week, randomized trial, daily oral orforglipron was associated with clinically significant weight reduction, with efficacy and safety similar to those of injectable GLP-1 receptor agonists. https://t.co/lNjqjAF5oc

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